NFL · Week 10 · 2026 Fantasy Preview

SEA at LV — Fantasy Preview

Top targets, injury updates, and defense vs position matchup data for Week 10 of the 2026 NFL season.

SEA

SEA · Away

LV · Home

Sunday, November 15, 2026

4:05 PM EST

Spread: LV -6

Fantasy Targets by Team

SEA Targets

Jaxon Smith-Njigba WR · SEA

Opp allows 9.3 pts/game to WR (#3 easiest)

19.8

avg pts (42g)

Sam Darnoldout QB · SEA

Opp allows 16.3 pts/game to QB (#1 easiest)

16.8

avg pts (40g)

Drew Lock QB · SEA

Opp allows 16.3 pts/game to QB (#1 easiest)

14.9

avg pts (8g)

Zach Charbonnet RB · SEA

Opp allows 9.4 pts/game to RB (#2 easiest)

avg pts (34g)

Tory Horton WR · SEA

Opp allows 9.3 pts/game to WR (#3 easiest)

avg pts (9g)

LV Targets

Brock Bowers TE · LV

Opp allows 8.1 pts/game to TE (#4 easiest)

16.1

avg pts (35g)

Ashton Jeanty RB · LV

Opp allows 9.6 pts/game to RB (#2 easiest)

15.1

avg pts (25g)

Kirk Cousins QB · LV

Opp allows 15.7 pts/game to QB (#1 easiest)

12.5

avg pts (24g)

Aidan O'Connell QB · LV

Opp allows 15.7 pts/game to QB (#1 easiest)

10.2

avg pts (10g)

Tre Tucker WR · LV

Opp allows 9 pts/game to WR (#3 easiest)

avg pts (39g)

Injury & Beat Reporter Signals

SEA

high Rashid Shaheed injury update

Shaheed is out again, with Tory Horton and Cooper Kupp expected to take most WR snaps alongside Jaxon Smith-Njigba. Drew…

high Charles Cross injury update

Cross will miss his second straight game while tending to a high-ankle sprain he suffered in Week 7 against Kansas City.…

high Uchenna Nwosu injury update

Nwosu sat out Monday's game versus the Bears with an ankle injury, and after missing practice Thursday and Friday, he'll…

high Michael Arroyo injury update

The Mariners expect Arroyo to be ready to play in games again by next April, so he's slated to get a late start to next …

high Nick Davila injury update

Davila's initial placement on the shelf was retroactive to Aug. 31, so his move to the 60-day IL will officially bring a…

high Colt Emerson injury update

The transaction frees up a spot on the 40-man roster for the return of Cooper Criswell from the 60-day IL. Emerson under…

high Thomas Booker IV injury update

Booker was limited in practice Wednesday, then sat out the sessions Thursday and Friday entirely. He's thus set to miss …

medium Darien Porter injury update

Porter continues to deal with the groin injury he suffered early in the first quarter of the Raiders' Week 8 win over th…

medium Dont'e Thornton Jr. injury update

Thornton was added to the injury report with an apparent back injury after opening the week as a full participant Wednes…

Defense vs Position Matchup

SEA defense — pts allowed

QB 15.7 avg pts

RB 9.6 avg pts

WR 9 avg pts

TE 8.1 avg pts

LV defense — pts allowed

QB 16.3 avg pts

RB 9.4 avg pts

WR 9.3 avg pts

TE 7.3 avg pts

Get a roster-specific verdict for this game

This is matchup context. PlayCaller knows your exact roster, scoring settings, and lineup options — and gives you a start/sit decision tailored to you, not a generic target list.

Try Free for 7 Days →

Frequently Asked Questions

Who should I start from the SEA vs LV game?

Top fantasy targets in this matchup: Jaxon Smith-Njigba and Brock Bowers. See the full target list and injury updates above.

Is this a good DFS game for Week 10?

The spread for this game is LV -6. Game environment (spread, total, weather) plus player-level targets and injury status are all shown on this page.

What is the fantasy matchup outlook for SEA players this week?

LV defense allows 9.4 pts/game to RBs and 9.3 pts/game to WRs. Historical matchup data above shows which positions are most exploitable.

More Week 10 matchup analysis

← Week 9 RB Rankings WR Rankings QB Rankings