PLAYCALLER
Get started free
Waiver WireDynastyMock DraftThe FeedPricingAPILog in
Home › Fantasy NFL › Week 10 Previews › HOU at CLE
NFL · Week 10 · 2026 Fantasy Preview

HOU at CLE — Fantasy Preview

Top targets, injury updates, and defense vs position matchup data for Week 10 of the 2026 NFL season.

HOU
HOU · Away
@
CLE
CLE · Home
Sunday, November 15, 2026
1:00 PM EST
Spread: CLE -4.5

Fantasy Targets by Team

HOU Targets
Nico Collins WR · HOU
Opp allows 9.8 pts/game to WR (#3 easiest)
16
avg pts (32g)
C.J. Stroud QB · HOU
Opp allows 15 pts/game to QB (#1 easiest)
15.2
avg pts (38g)
David Montgomery RB · HOU
Opp allows 9.9 pts/game to RB (#2 easiest)
12.1
avg pts (36g)
Tank Dell WR · HOU
Opp allows 9.8 pts/game to WR (#3 easiest)
10.4
avg pts (14g)
Jawhar Jordan RB · HOU
Opp allows 9.9 pts/game to RB (#2 easiest)
10.4
avg pts (4g)
CLE Targets
Deshaun Watson QB · CLE
Opp allows 15.5 pts/game to QB (#1 easiest)
13.4
avg pts (15g)
Quinshon Judkins RB · CLE
Opp allows 9.7 pts/game to RB (#3 easiest)
12.2
avg pts (21g)
Shedeur Sanders QB · CLE
Opp allows 15.5 pts/game to QB (#1 easiest)
11.9
avg pts (8g)
Harold Fannin TE · CLE
Opp allows 6.7 pts/game to TE (#4 easiest)
11.7
avg pts (16g)
Harold Fannin Jr. TE · CLE
Opp allows 6.7 pts/game to TE (#4 easiest)
11.3
avg pts (8g)

Injury & Beat Reporter Signals

HOU
high Clint Capela injury update
The veteran big man is managing a sprained right ankle, which is costing him a third consecutive contest. His next chanc…
high Brandon Walter injury update
Walter is one of three Astros starters in Florida rehabbing from Tommy John surgery, though Hayden Wesneski (elbow) and …
high Carlos Correa injury update
The Astros announced Wednesday that Correa won't be able to make it back before the end of the season because he couldn'…
high Jaylin Noel injury update
Noel was forced out of this past Sunday's 27-21 overtime loss to the Giants after going down with the toe injury with ju…
high Joey Loperfido injury update
The expectation is that Loperfido will be delayed at the beginning of spring training, but it's unclear whether he will …
high Reed Blankenship injury update
Blankenship suffered a concussion in Week 6 against Jacksonville, and he had surgery on his hand not long after that con…
CLE
high Colin Holderman injury update
The operation was successful, and Holderman is expected to be 100 percent in time for spring training. Holderman posted …
high Kahlil Watson injury update
It's not clear how long Watson had been dealing with a sports hernia, but the decision to have surgery was made after he…
high Jarrett Allen injury update
Allen missed Friday's game against the 76ers and will also miss the second leg of the back-to-back set against the reign…
high Sam Merrill injury update
Merrill exited Friday's game against the 76ers due to an elbow injury, and the Cavaliers are taking a cautious approach …
high Andrew Walters injury update
Walters had right lat surgery last June, and he is now slated for another extended rehab that will rule him out until th…
high Jaylon Tyson injury update
Tyson continues to recover from a sprained right ankle, and he'll miss the second leg of this back-to-back set after not…

Defense vs Position Matchup

HOU defense — pts allowed
QB 15.5 avg pts
RB 9.7 avg pts
WR 10.2 avg pts
TE 6.7 avg pts
CLE defense — pts allowed
QB 15 avg pts
RB 9.9 avg pts
WR 9.8 avg pts
TE 6.8 avg pts

Get a roster-specific verdict for this game

This is matchup context. PlayCaller knows your exact roster, scoring settings, and lineup options — and gives you a start/sit decision tailored to you, not a generic target list.

Try Free for 7 Days →

Frequently Asked Questions

Who should I start from the HOU vs CLE game?
Top fantasy targets in this matchup: Nico Collins and Deshaun Watson. See the full target list and injury updates above.
Is this a good DFS game for Week 10?
The spread for this game is CLE -4.5. Game environment (spread, total, weather) plus player-level targets and injury status are all shown on this page.
What is the fantasy matchup outlook for HOU players this week?
CLE defense allows 9.9 pts/game to RBs and 9.8 pts/game to WRs. Historical matchup data above shows which positions are most exploitable.

More Week 10 matchup analysis

← Week 9 RB Rankings WR Rankings QB Rankings