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NFL · Week 1 · 2025

NFL Week 1 2025 Start/Sit: Fantasy Recommendations

Published July 4, 2026 · Based on real 2025 box score data

Week 1 of the 2025 NFL season delivered explosive performances across the board, with dual-threat quarterbacks and pass-catchers dominating fantasy lineups. The week showcased several strong performers who delivered solid production, while a handful of starters underperformed relative to expectations.

Top Performers: Week 1 Leaders

Josh Allen (BUF) - QB: 38.8 pts

Allen completed 394 passing yards with 2 touchdown passes and added 30 rushing yards with 2 rushing touchdowns, playing all 100% of Buffalo's snaps. His combined passing and rushing production gave him the highest score of the week at the quarterback position.

Derrick Henry (BAL) - RB: 29.2 pts

Henry dominated on the ground with 169 rushing yards and 2 rushing touchdowns, while adding 1 reception for 13 yards across 57% of snaps. His rushing performance led all running backs for the week.

Zay Flowers (BAL) - WR: 28.1 pts

Flowers caught 7 passes for 143 yards and 1 touchdown while playing 90% of snaps, adding 8 rushing yards. He finished second overall for the week behind Josh Allen.

Keon Coleman (BUF) - WR: 25.2 pts

Coleman hauled in 8 catches for 112 yards and 1 touchdown at 88% snap participation, establishing himself as a primary receiving target in Buffalo's offense.

Solid Performers: Secondary Options

Underperformers: Below Expectations

For future weeks, consider using lineup optimization tools to maximize your fantasy advantages.

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