Fantasy matchup analysis — how many points the Bills allow to running backs. Updated through the 2025 season. Use this to identify streamers and make start/sit decisions.
Players who have historically scored most against the Buffalo Bills defense:
Last 10 games running backs faced the Buffalo Bills (2024–2025 seasons):
| Game | Player | Fantasy Pts |
|---|---|---|
| S2025 Wk18 | Khalil Herbert UNK |
5.6 |
| S2025 Wk18 | Kene Nwangwu NYJ |
1.8 |
| S2025 Wk18 | Andrew Beck NYJ |
7.2 |
| S2025 Wk17 | Saquon Barkley PHI |
6.8 |
| S2025 Wk17 | Tank Bigsby PHI |
1.9 |
| S2025 Wk16 | Trayveon Williams UNK |
9.5 |
| S2025 Wk16 | Quinshon Judkins CLE |
10.1 |
| S2025 Wk16 | Raheim Sanders CLE |
5.6 |
| S2025 Wk15 | Rhamondre Stevenson NE |
10.7 |
| S2025 Wk15 | TreVeyon Henderson NE |
30.1 |
This is matchup context, not a personalized recommendation. Connect your Sleeper, ESPN, or Yahoo league and PlayCaller's AI gives you a start/sit decision based on your exact roster, league scoring, and this week's matchup.
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