Fantasy matchup analysis — how many points the Colts allow to quarterbacks. Updated through the 2025 season. Use this to identify streamers and make start/sit decisions.
Players who have historically scored most against the Indianapolis Colts defense:
Last 10 games quarterbacks faced the Indianapolis Colts (2024–2025 seasons):
| Game | Player | Fantasy Pts |
|---|---|---|
| S2025 Wk18 | Davis Mills HOU |
2.6 |
| S2025 Wk18 | C.J. Stroud HOU |
17.3 |
| S2025 Wk17 | Trevor Lawrence JAX |
24.1 |
| S2025 Wk16 | Brock Purdy SF |
31.9 |
| S2025 Wk15 | Sam Darnold SEA |
11.3 |
| S2025 Wk14 | Trevor Lawrence JAX |
19.4 |
| S2025 Wk13 | C.J. Stroud HOU |
10 |
| S2025 Wk12 | Patrick Mahomes KC |
18.1 |
| S2025 Wk10 | Michael Penix ATL |
11 |
| S2025 Wk10 | Tua Tagovailoa ATL |
12.8 |
This is matchup context, not a personalized recommendation. Connect your Sleeper, ESPN, or Yahoo league and PlayCaller's AI gives you a start/sit decision based on your exact roster, league scoring, and this week's matchup.
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