NFL · Week 3 · 2026 Fantasy Preview

LAC at BUF — Fantasy Preview

Top targets, injury updates, and defense vs position matchup data for Week 3 of the 2026 NFL season.

LAC

LAC · Away

BUF

BUF · Home

Sunday, September 27, 2026

1:00 PM EDT

Fantasy Targets by Team

LAC Targets

Justin Herbert QB · LAC

Opp allows 14.4 pts/game to QB (#1 easiest)

17.8

avg pts (33g)

Omarion Hampton RB · LAC

Opp allows 11.3 pts/game to RB (#2 easiest)

15.1

avg pts (9g)

Quentin Johnston WR · LAC

Opp allows 9.2 pts/game to WR (#3 easiest)

13.3

avg pts (26g)

Ladd McConkeyquestionable WR · LAC

Opp allows 9.2 pts/game to WR (#3 easiest)

13.2

avg pts (32g)

David Njoku TE · LAC

Opp allows 5.8 pts/game to TE (#4 easiest)

10.7

avg pts (22g)

BUF Targets

Josh Allen QB · BUF

Opp allows 15.9 pts/game to QB (#1 easiest)

23.7

avg pts (32g)

Josh Allen QB · BUF

Opp allows 15.9 pts/game to QB (#1 easiest)

23.7

avg pts (32g)

James Cook RB · BUF

Opp allows 9.4 pts/game to RB (#2 easiest)

17.2

avg pts (33g)

DJ Moore WR · BUF

Opp allows 8.7 pts/game to WR (#3 easiest)

12.7

avg pts (32g)

DJ Moore WR · BUF

Opp allows 8.7 pts/game to WR (#3 easiest)

12.7

avg pts (32g)

Injury & Beat Reporter Signals

LAC

No active signals

BUF

medium DJ Moore role expansion

Moore was traded to Buffalo from Chicago for a 2nd-round pick to provide Josh Allen a proven No. 1 receiver. He faces le…

medium Khalil Shakir role reduction

Shakir led Bills with 95 targets in 2025 (72-719-4), but DJ Moore's acquisition as the top WR target should reduce his v…

medium Josh Allen return from injury

Allen suffered a fifth metatarsal fracture in his right foot post-Week 16 and underwent surgery with 8-10 week recovery …

medium Dalton Kincaid return from injury

Kincaid avoided offseason surgery for his PCL injury and reports feeling excellent heading into 2026. He should maintain…

medium Khalil Shakir role reduction

After leading the Bills with 95 targets in 2025, Shakir will see reduced volume as Josh Allen's primary target with DJ M…

medium DJ Moore role expansion

The 29-year-old veteran was acquired from Chicago for a second-round pick to provide Josh Allen a proven No. 1 receiver.…

Defense vs Position Matchup

LAC defense — pts allowed

QB 15.9 avg pts

RB 9.4 avg pts

WR 8.7 avg pts

TE 6.4 avg pts

BUF defense — pts allowed

QB 14.4 avg pts

RB 11.3 avg pts

WR 9.2 avg pts

TE 5.8 avg pts

Get a roster-specific verdict for this game

This is matchup context. PlayCaller knows your exact roster, scoring settings, and lineup options — and gives you a start/sit decision tailored to you, not a generic target list.

Try Free for 7 Days →

Frequently Asked Questions

Who should I start from the LAC vs BUF game?

Top fantasy targets in this matchup: Justin Herbert and Josh Allen. See the full target list and injury updates above.

Is this a good DFS game for Week 3?

Check back closer to game time for spread, total, and projected scoring environment data. Use the player targets above to identify DFS value plays.

What is the fantasy matchup outlook for LAC players this week?

BUF defense allows 11.3 pts/game to RBs and 9.2 pts/game to WRs. Historical matchup data above shows which positions are most exploitable.

More Week 3 matchup analysis

← Week 2 RB Rankings WR Rankings QB Rankings