NFL · Week 18 · 2026 Fantasy Preview

SF at ARI — Fantasy Preview

Top targets, injury updates, and defense vs position matchup data for Week 18 of the 2026 NFL season.

SF · Away

ARI

ARI · Home

Sunday, January 10, 2027

12:00 AM EST

Fantasy Targets by Team

SF Targets

Christian McCaffrey RB · SF

Opp allows 11.2 pts/game to RB (#2 easiest)

22.1

avg pts (21g)

Brock Purdy QB · SF

Opp allows 15.7 pts/game to QB (#1 easiest)

19.4

avg pts (24g)

George Kittle TE · SF

Opp allows 7.3 pts/game to TE (#4 easiest)

15.9

avg pts (25g)

Mike Evans WR · SF

Opp allows 9.3 pts/game to WR (#3 easiest)

15.5

avg pts (21g)

Mac Jones QB · SF

Opp allows 15.7 pts/game to QB (#1 easiest)

15.1

avg pts (16g)

ARI Targets

Trey McBride TE · ARI

Opp allows 7.8 pts/game to TE (#4 easiest)

17.1

avg pts (33g)

Jacoby Brissett QB · ARI

Opp allows 15.9 pts/game to QB (#1 easiest)

15.6

avg pts (18g)

James Conner RB · ARI

Opp allows 10.8 pts/game to RB (#2 easiest)

15.2

avg pts (19g)

Marvin Harrison WR · ARI

Opp allows 9.3 pts/game to WR (#3 easiest)

avg pts (27g)

Michael Wilson WR · ARI

Opp allows 9.3 pts/game to WR (#3 easiest)

10.8

avg pts (32g)

Injury & Beat Reporter Signals

No active signals

ARI

medium Zac Gallen return from injury

Right-hander received clearance from Dr. Neal ElAttrache to resume throwing after second opinion. No estimated return da…

medium Michael Soroka return from injury

Right-hander scheduled for two-inning rehab outing Saturday. Expected to complete at least one rehab start before early-…

medium Justin Martinez return from injury

Former closer advancing through rehab (bullpen session, bridge games) with late August/September return expected. Will n…

medium Marvin Harrison Jr. return from injury

Harrison missed 5 games in 2025 due to heel injuries, concussion, and appendicitis but confirmed he's healthy for OTAs w…

medium James Conner return from injury

Conner has fully recovered from his 2025 ankle injury but faces competition from first-rounder Jeremiyah Love, Tyler All…

medium Michael Wilson role reduction

After 1,000-yard breakout in 2025, Wilson faces reduced opportunity with new coaching staff, return of Jeremiah Love at …

Defense vs Position Matchup

SF defense — pts allowed

QB 15.9 avg pts

RB 10.8 avg pts

WR 9.3 avg pts

TE 7.8 avg pts

ARI defense — pts allowed

QB 15.7 avg pts

RB 11.2 avg pts

WR 9.3 avg pts

TE 7.3 avg pts

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Frequently Asked Questions

Who should I start from the SF vs ARI game?

Top fantasy targets in this matchup: Christian McCaffrey and Trey McBride. See the full target list and injury updates above.

Is this a good DFS game for Week 18?

Check back closer to game time for spread, total, and projected scoring environment data. Use the player targets above to identify DFS value plays.

What is the fantasy matchup outlook for SF players this week?

ARI defense allows 11.2 pts/game to RBs and 9.3 pts/game to WRs. Historical matchup data above shows which positions are most exploitable.

More Week 18 matchup analysis

← Week 17 RB Rankings WR Rankings QB Rankings