NFL · Week 1 · 2026 Fantasy Preview

BUF at HOU — Fantasy Preview

Top targets, injury updates, and defense vs position matchup data for Week 1 of the 2026 NFL season.

BUF

BUF · Away

HOU

HOU · Home

Sunday, September 13, 2026

1:00 PM EDT

Fantasy Targets by Team

BUF Targets

Josh Allen QB · BUF

Opp allows 15.4 pts/game to QB (#1 easiest)

23.7

avg pts (32g)

Josh Allen QB · BUF

Opp allows 15.4 pts/game to QB (#1 easiest)

23.7

avg pts (32g)

James Cook RB · BUF

Opp allows 9.5 pts/game to RB (#3 easiest)

17.2

avg pts (33g)

DJ Moore WR · BUF

Opp allows 10 pts/game to WR (#2 easiest)

12.7

avg pts (32g)

DJ Moore WR · BUF

Opp allows 10 pts/game to WR (#2 easiest)

12.7

avg pts (32g)

HOU Targets

Nico Collins WR · HOU

Opp allows 9.2 pts/game to WR (#3 easiest)

16.2

avg pts (27g)

C.J. Stroud QB · HOU

Opp allows 14.4 pts/game to QB (#1 easiest)

14.5

avg pts (31g)

David Montgomery RB · HOU

Opp allows 11.3 pts/game to RB (#2 easiest)

12.5

avg pts (31g)

Tank Dellquestionable WR · HOU

Opp allows 9.2 pts/game to WR (#3 easiest)

10.8

avg pts (13g)

Woody Marks RB · HOU

Opp allows 11.3 pts/game to RB (#2 easiest)

10.1

avg pts (15g)

Injury & Beat Reporter Signals

BUF

medium DJ Moore role expansion

Moore was traded to Buffalo from Chicago for a 2nd-round pick to provide Josh Allen a proven No. 1 receiver. He faces le…

medium Khalil Shakir role reduction

Shakir led Bills with 95 targets in 2025 (72-719-4), but DJ Moore's acquisition as the top WR target should reduce his v…

medium Josh Allen return from injury

Allen suffered a fifth metatarsal fracture in his right foot post-Week 16 and underwent surgery with 8-10 week recovery …

medium Dalton Kincaid return from injury

Kincaid avoided offseason surgery for his PCL injury and reports feeling excellent heading into 2026. He should maintain…

medium Khalil Shakir role reduction

After leading the Bills with 95 targets in 2025, Shakir will see reduced volume as Josh Allen's primary target with DJ M…

medium DJ Moore role expansion

The 29-year-old veteran was acquired from Chicago for a second-round pick to provide Josh Allen a proven No. 1 receiver.…

HOU

high Kevin Durant injury update

The Rockets previously listed Durant as doubtful for this contest. Houston has all the momentum in this series right no…

high Steven Adams injury update

Adams was already viewed as out indefinitely with a Grade 3 sprain, but now he won't be able to return during the 2025-2…

medium Fred VanVleet return from injury

VanVleet missed the entire 2025-26 season with an ACL tear but shows optimism for Opening Night availability. Monitor pr…

Defense vs Position Matchup

BUF defense — pts allowed

QB 14.4 avg pts

RB 11.3 avg pts

WR 9.2 avg pts

TE 5.8 avg pts

HOU defense — pts allowed

QB 15.4 avg pts

RB 9.5 avg pts

WR 10 avg pts

TE 6.7 avg pts

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Frequently Asked Questions

Who should I start from the BUF vs HOU game?

Top fantasy targets in this matchup: Josh Allen and Nico Collins. See the full target list and injury updates above.

Is this a good DFS game for Week 1?

Check back closer to game time for spread, total, and projected scoring environment data. Use the player targets above to identify DFS value plays.

What is the fantasy matchup outlook for BUF players this week?

HOU defense allows 9.5 pts/game to RBs and 10 pts/game to WRs. Historical matchup data above shows which positions are most exploitable.

More Week 1 matchup analysis

← Week 18 RB Rankings WR Rankings QB Rankings