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NFL · Week 16 · 2025

NFL Week 16 2025 Start/Sit: Fantasy Recommendations

Published July 4, 2026 · Based on real 2025 box score data

Week 16 of the 2025 NFL season delivered strong fantasy performances across multiple positions, with several players exceeding 30 fantasy points. The standout week rewarded managers who started the top performers heading into the stretch run.

Must-Starts: Week 16 Top Performers

Puka Nacua (LAR) — WR: 46.5 pts

Puka Nacua hauled in 12 catches for 225 yards and 2 touchdowns on a 78% snap rate, putting together one of the most dominant wide receiver performances of the week. His 12 receptions and 225 receiving yards led all pass catchers, making him a clear centerpiece in any winning lineup.

Brock Purdy (SF) — QB: 31.9 pts

Brock Purdy completed 295 passing yards with 5 touchdowns and maintained a 95% snap rate, delivering one of the week's most efficient quarterback outings. His five passing touchdowns alone justified a start, representing the highest TD total from any quarterback in Week 16.

Chase Brown (CIN) — RB: 32.9 pts

Chase Brown accumulated 66 rushing yards and added 4 receptions for 43 yards while scoring 3 total touchdowns (1 rushing, 2 receiving). His multi-dimensional production made him the RB1 for the week, combining both ground and air game contributions in Cincinnati's offense.

Chris Olave (NO) — WR: 36.8 pts

Chris Olave caught 10 passes for 148 yards and 2 touchdowns on a 78% snap rate, establishing himself as the focal point of the New Orleans passing attack. His target volume of 10 receptions combined with 2 touchdown receptions delivered a dominant fantasy performance.

Strong Starts: Reliable Options

Tough Sits: Disappointing Weeks

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